4LSC2016 – UNC3866
Catalog Number: 4LSC2016
CAS #: 1872382-47-2 (free base)Â / 1872382-48-3 (TFA salt)
Name: UNC3866, methyl N2-(4-(tert-butyl)benzoyl)-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serinate.
Product Description: A cellular chemical probe targeting the chromodomains of Polycomb Repressive Complex 1. UNC3866, a potent antagonist of the methyllysine (Kme) reading function of the Polycomb CBX and CDY families of chromodomains.
References:
Stuckey, J. I., Dickson, B. M., Cheng, N., Liu, Y., Norris, J. L., Cholensky, S. H., … Frye, S. V. (2016). A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nature Chemical Biology, 12(3), 180-187. DOI: 10.1038/nchembio.2007
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