4LSC2025 Macimorelin acetate CAS# 945212-59-9
CAS #: 945212-59-9 (acetate salt)
Related CAS # 381231-18-1 (free base)
Name: Macimorelin acetate, Macrilen, ARD-07, AEZS-130, JMV1843, 2-amino-N-((R)-1-(((R)-1-formamido-2-(1H-indol-3-yl)ethyl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-2-methylpropanamide acetate
Macimorelin (Macrilen) has been developed by Æterna Zentaris and has been approved by the FDA for use in the diagnosis of adult growth hormone deficiency (AGHD). Macimorelin is a mimic of ghrelin, a growth hormone secretagogue (GHS or GHRP). It binds to the growth hormone secretagogue receptor (GHSR) causing release of growth hormone from the pituitary gland.
Clinical chemistry, diagnostic tools & biomarkers.
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- Molecular Formula: C28H34N6O5 (acetate salt), C26H30N6O3 (free base)
Molecular Weight: 534.62 g/mol (acetate salt), 474.57 g/mol (free base)
- Specification: Minimum purity: 95.0 %
- Packing Size: 5mg, 10mg, 100mg, bulk (gram scale)
- Solubility: methanol, water, acetonitrile
- Physical Appearance: white solid
- Storage: 4°C (long term storage)
- HS Code: 284590
Macimorelin as a Diagnostic Test for Adult GH Deficiency. Garcia et al. 2018, J. Clin. Endocrinol . Metab. , 103(8):3083-3093. doi: 10.1210/jc.2018-00665
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