4LSC2038 – R-IMPP

Catalog Number: 4LSC2038

CAS #: None

Name: (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide, R-IMPP

Molecular Formula: C24H27N3O2

Molecular Weight: 389.5 g/mol


Minimum purity: 95.0 %

Product Description:

4LSC2038 (R-IMPP) is a small-molecule Anti-secretagogue of PCSK9 that targets the 80S Ribosome to Inhibit PCSK9 Protein Translation. R-IMPP promotes uptake of LDL-C in hepatoma cells by increasing LDL-R levels, PCSK9 translation is blocked by R-IMPP in a sequence-dependent manner.


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