4LSC2040 – WNK463

SKU: 4LSC2040 Category: Tag:

Catalog Number: 4LSC2040

CAS #: None

Name: N-(tert-butyl)-1-(1-(5-(5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl)pyridin-2-yl)piperidin-4-yl)-1H-imidazole-5-carboxamide, WNK463

Molecular Formula: C21H24F3N7O2

Molecular Weight: 463.46 g/mol

Specification:

Minimum purity: 95.0 %

Product Description:

4LSC2040 (WNK463) is a the first orally bioavailable pan-WNK-kinase inhibitor that exploits unique structural features of the WNK kinases for both affinity and kinase selectivity. In rodent models of hypertension, WNK463 affects blood pressure and body fluid and
electro-lyte homeostasis, consistent with WNK-kinase-associated physiology and pathophysiology.

C21H24F3N7O2