Catalog Number: 4LSC2221
CAS #: 1492952-76-7
Name: (R)-N-(4-(chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-5-yl)nicotinamide, Asciminib, UNII-L1F3R18W77, ABL001, ABL-001, L1F3R18W77
Molecular Formula: C20H18ClN5O3F2
Molecular Weight: 449.84 g/mol
Minimum purity: 95.0 %
Asciminib, also known as ABL001, is a potent allosteric inhibitor of BCR-ABL. ABL001 prevents emergence of resistant disease when administered in combination with nilotinib in an in vivo murine model of chronic myeloid leukemia.
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