Catalog Number: 4LSC2469
CAS #: 1056634-68-4, 1380317-28-1 (Momelotinib Dihydrochloride)
Name: CYT387, N-(cyanomethyl)-4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzamide
Molecular Formula: C23H22N6O2
Molecular Weight: 441.47 g/mol
Minimum purity: 95.0 %
Momelotinib (CYT387) is an ATP-competitive small molecule that potently inhibits JAK1/JAK2 kinases (IC(50)=11 and 18 nM, respectively), with significantly less activity against other kinases, including JAK3 (IC(50)=155 nM).
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