4LSC2533 [D9]-Dabrafenib

SKU: 4LSC2533 Categories: , Tags: , , ,

Catalog Number: 4LSC2533
CAS #: N/A
Related CAS #: 1195765-45-7 (unlabeled)
Name: [D9]-Dabrafenib; N-(3-(5-(2-aminopyrimidin-4-yl)-2-(2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide

Dabrafenib (GSK2118436) is a drug for the treatment of cancers associated with a mutated version of the gene BRAF. Dabrafenib acts as an inhibitor of the associated enzyme B-Raf, which plays a role in the regulation of cell growth.

Stable isotope labeled Dabrafenib is intended for use as an internal standard for the quantification of Dabrafenib by LC or GC-mass spectrometry.

If the number, nature and/or location of stable isotope label atoms (D, 15N, 13C) in this molecule don’t fit with your application, don’t hesitate to contact us to discuss your specific needs.

Keywords:

Stable isotope labeled active pharmaceutical ingredient (API), stable isotope dilution analysis, internal standard, stable isotope labeled standard (SIL), therapeutic drug monitoring (TDM), quantitative bioanalytical method validation, clinical diagnosis, LC/MS method validation, quantitative proteomics, selective reaction monitoring (SRM), multiple reaction monitoring (MRM), peptide based quantitative proteomics, custom stable isotope labeled (SIL) peptide, diagnostic breath test, clinical chemistry, diagnostic tools & biomarkers.

  • Molecular Formula: C23H11D9F3N5O2S2
  • Molecular Weight: 528.62 g/mol
  • Specification:
    Minimum chemical purity: 95.0 %
    Minimum Isotopic Enrichment: 2H ≥98 %
  • Solubility: Methanol (MeOH), Dimethylsulfoxide (DMSO),
  • HS Code: 284590

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