4LSC2563 – Macrocyclic inhibitor of the PD-1/PD-L1 interaction

SKU: 4LSC2563 Category: Tags: ,

Catalog Number: 4LSC2563

CAS #: N/A

Name: Ac(1)-Phe-N(Me)Ala-Asn-Pro-His-Leu-Sar-Trp-Ser-Trp-N(Me)Nle-N(Me)Nle-Arg-Cys(1)-Gly-NH2

Molecular Formula: C89H126N24O18S

Molecular Weight: 1 852.2 g/mol

Specification: Minimum purity: 95.0 %

Product Description: 4LSC2563 is a s a Macrocyclic inhibitor  of PD-1/PD-L1 (Programmed Death-1/Programmed Death-Ligand 1) interaction with IC50 of 9 nM (HTRF Human PD-1/PD-L1 binding assay)

References: WO 2014/151634A1 Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions

 

 

 


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