4LSC2565 PF-9366 CAS# 72882-78-1

Catalog Number: 4LSC2565
CAS #: 72882-78-1
Name: PF-9366, 2-(7-chloro-5-phenyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethan-1-amine

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PF-9366 is an allosteric Mat2A (methionine adenosyltransferase enzyme) inhibitor that inhibits cellular SAM (S-adenosylmethionine) synthesis with submicromolar potency.

  • Molecular Formula: C20H19ClN4
  • Molecular Weight: 350.85 g/mol
  • Specification: Minimum purity: 95.0 %

Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A. Nature Chemical Biology, 13, 785-792, 2017. doi:10.1038/nchembio.2384


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