4LSC2566 [13C6]-Tobramycin

Catalog Number: 4LSC2566
CAS #: N/A
Related CAS #: 32986-56-4 (unlabeled)
Name: [13C6]-Tobramycin, 4-amino-2-(((1S,2R,3R,4S,6R)-4,6-diamino-3-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-6-(hydroxy-l2-methyl-13C)-2H-2l3,3l3,4l3,5l3,6l3-pyran-3,5(4H,6H)-diol-2,3,4,5,6-13C5

Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas.

Stable isotope labeled Tobramycin is intended for use as an internal standard for the quantification of Tobramycin by LC or GC-mass spectrometry, an alternative to immunoassay based quantification.

If the number, nature and/or location of stable isotope label atoms (D, 15N, 13C) in this molecule don’t fit with your application, don’t hesitate to contact us to discuss your specific needs.

Keywords:

Stable isotope labeled active pharmaceutical ingredient (API), stable isotope dilution analysis, internal standard, stable isotope labeled standard (SIL), therapeutic drug monitoring (TDM), quantitative bioanalytical method validation, clinical diagnosis, LC/MS method validation, diagnostic breath test, clinical chemistry, diagnostic tools & biomarkers.

  • Molecular Formula: C1213C6H30N5O9
  • Molecular Weight: 466.42 g/mol
  • Specification:
    Minimum chemical purity: 95.0 %
    Minimum Isotopic Enrichment: 13C ≥98 %
  • Solubility: Water (H2O, 50mg/mL), Dimethylsulfoxide (DMSO)
  • Packing size: 1, 5, 10, 25, 50mg, custom packing size on request
  • HS Code: 284590
 
Tobramycin Level Monitoring – Discrepancy between immunoassays. C.E. Shalapay et al. Clinical Chemistry, 2015, 61, 10, S214 – Abstract B-301 from AACC (American Association for Clinical Chemistry) 2015 annual meeting.
 
 

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