4LSC2737 [13C6]-Trametinib

Catalog Number: 4LSC2737
CAS #: N/A
Related CAS #: 871700-17-3 (unlabeled)
Name: [13C6]-Trametinib; N-(3-(3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl-1,2,3,4,5,6-13C6)acetamide

Trametinib is an anti-cancer drug. This a reversible inhibitor of mitogen-activated extracellular signal-regulated kinase (MEK1 and MEK2). Trametinib had good results for metastatic melanoma carrying the BRAF V600E mutation.

Stable isotope labeled Trametinib is intended for use as an internal standard for the quantification of Trametinib by LC or GC-mass spectrometry.

If the number, nature and/or location of stable isotope label atoms (D, 15N, 13C) in this molecule don’t fit with your application, don’t hesitate to contact us to discuss your specific needs.

Keywords:

Stable isotope labeled active pharmaceutical ingredient (API), stable isotope dilution analysis, internal standard, stable isotope labeled standard (SIL), therapeutic drug monitoring (TDM), quantitative bioanalytical method validation, clinical diagnosis, LC/MS method validation, quantitative proteomics, selective reaction monitoring (SRM), multiple reaction monitoring (MRM), peptide based quantitative proteomics, custom stable isotope labeled (SIL) peptide, diagnostic breath test, clinical chemistry, diagnostic tools & biomarkers.

  • Molecular Formula: C2013C6H23FIN5O4
  • Molecular Weight: 621.4 g/mol
  • Specification:
    Minimum chemical purity: 95.0 %
    Minimum Isotopic Enrichment: 13C ≥99 %
  • Solubility: Methanol (MeOH), Dimethylsulfoxide (DMSO),
  • HS Code: 284590

N/A