4LSC2778 GNE-6640 CAS# 2009273-67-8

Catalog #: 4LSC2778
CAS #: 2009273-67-8
Name: GNE-6640; 4-(2-amino-4-ethyl-5-(1H-indazol-5-yl)pyridin-3-yl)phenol

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GNE-6640 is a selective USP7 (Ubiquitin-specific-processing protease 7) inhibitor, it induces tumour cell death and enhances cytotoxicity with chemotherapeutic agents and targeted compounds including PIM kinase inhibitors.

  • Molecular Formula: C20H18N4O
  • Molecular Weight: 330.39 g/mol
  • Specification: Minimum purity: 95.0 %

USP7 small-molecule inhibitors interfere with ubiquitin binding. Kategaya et al., 2017, Nature, 550(7677):534-538. doi: 10.1038/nature24006

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