4LSC2779 GNE-6776 CAS# 2009273-60-1
Catalog #: 4LSC2779
CAS #: 2009273-60-1
Name: GN-6776; 6′-amino-4′-ethyl-5′-(4-hydroxyphenyl)-N-methyl-[3,3′-bipyridine]-6-carboxamide
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GNE-6776 is a selective USP7 (Ubiquitin-specific-processing protease 7) inhibitor, it induces tumour cell death and enhances cytotoxicity with chemotherapeutic agents and targeted compounds including PIM kinase inhibitors.
- Molecular Formula: C20H20N4O2
- Molecular Weight: 348.41 g/mol
- Specification: Minimum purity: 95.0 %
USP7 small-molecule inhibitors interfere with ubiquitin binding. Kategaya et al., 2017, Nature, 550(7677):534-538. doi: 10.1038/nature24006
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