4LSC2785 FT827 CAS# 1959537-86-0

Catalog #: 4LSC2785
CAS #: 1959537-86-0
Name: FT827; N-(4′-(4-hydroxy-4-((1-methyl-4-oxo-1,4-dihydro-5H-pyrazolo[3,4-d]pyrimidin-5-yl)methyl)piperidine-1-carbonyl)-[1,1′-biphenyl]-2-yl)ethenesulfonamide

FT827 is a covalent USP7 inhibitor with high affinity (nanomolar-potency) and specificity in vitro and within human cells.

  • Molecular Formula: C27H28N6O5S
  • Molecular Weight: 548.62 g/mol
  • Specification: Minimum purity: 95.0 %

Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Turnbull AP, et al.  2017, Nature. Oct 26;550(7677):481-486. doi: 10.1038/nature24451

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