4LSC2844 [D5]-Ibrutinib

Catalog Number: 4LSC2844
CAS #: N/A
Related CAS #: 936563-96-1 (unlabeled)
Name: [D5]-Ibrutinib; (R)-1-(3-(4-amino-3-(4-(phenoxy-d5)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)but-3-en-1-one

Ibrutinib is a Bruton tyrosine kinase (BTK) inhibitor used to treat mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL)/small lymphocityc lymphoma (SLL) and Waldenström’s macroglobulinemia, a form of non-Hodgkin’s lymphoma. Stable isotope labeled Ibrutinib is intended for use as an internal standard for the quantification of Ibrutinib by LC or GC-mass spectrometry.

If the number, nature and/or location of stable isotope label atoms (D, 15N, 13C) in this molecule don’t fit with your application, don’t hesitate to contact us to discuss your specific needs.

Keywords:

Stable isotope labeled active pharmaceutical ingredient (API), stable isotope dilution analysis, internal standard, stable isotope labeled standard (SIL), therapeutic drug monitoring (TDM), quantitative bioanalytical method validation, clinical diagnosis, LC/MS method validation, quantitative proteomics, selective reaction monitoring (SRM), multiple reaction monitoring (MRM), peptide based quantitative proteomics, custom stable isotope labeled (SIL) peptide, diagnostic breath test, clinical chemistry, diagnostic tools & biomarkers.

  • Molecular Formula: C25H19D5N6O2
  • Molecular Weight: 445.54 g/mol
  • Specification:
    Minimum chemical purity: 95.0 %
    Minimum Isotopic Enrichment: 2H ≥98 %
  • Solubility: Methanol (MeOH), Dimethylsulfoxide (DMSO),
  • HS Code: 284590

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