4LSC2955 (R)-3-(4-(aminomethyl)phenyl)-6-((4-hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)-2-methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

Catalog #: 4LSC2955
CAS #: 2196243-57-7
Name: (R)-3-(4-(aminomethyl)phenyl)-6-((4-hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)-2-methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

(R)-3-(4-(aminomethyl)phenyl)-6-((4-hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)-2-methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one is a potent and selective USP7 (ubiquitin-specific protease 7)  inhibitor.

  • Molecular Formula: C29H34N6O3
  • Molecular Weight: 514.63 g/mol
  • Specification: Minimum purity: 95.0 %

Discovery and characterization of highly potent and selective allosteric USP7 inhibitors. Gavory et al., 2018, Nature Chemical Biology, 14, 118–125. doi: 10.1038/nchembio.2528


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