4LSC2881 [D8]-MMAE / [D8]-Monomethyl auristatin E
Catalog #: 4LSC2881
CAS #: N/A
Related CAS #: 474645-27-7 (unlabeled)
Name: [D8]-MMAE, [D8]-Monomethyl auristatin E
Monomethyl auristatin E (MMAE) is a synthetic antineoplastic agent, a very potent anti-mitotic agent that inhibits cell division by blocking the polymerisation of tubulin. Because of its toxicity, it cannot be used as a drug itself; instead, it is linked to a monoclonal antibody (mAB) which directs it to the cancer cells.
Stable isotope labeled MMAE is intended for use as an internal standard for the quantification of MMAE by LC/MS.
If the number, nature and/or location of stable isotope label atoms (D, 15N, 13C) in this molecule don’t fit with your application, don’t hesitate to contact us to discuss your specific needs.
Stable isotope labeled active pharmaceutical ingredient (API), stable isotope dilution analysis, internal standard, stable isotope labeled standard (SIL), therapeutic drug monitoring (TDM), quantitative bioanalytical method validation, clinical diagnostic, LC/MS method validation, ADCs cytotoxin.