4LSC2956 ML-792 CAS# 1644342-14-2
CAS #: 1644342-14-2
Name: ML-792; ((1R,2S,4R)-4-((5-(1-(3-bromobenzyl)-1H-pyrazole-3-carbonyl)pyrimidin-4-yl)amino)-2-hydroxycyclopentyl)methyl sulfamate
ML-792 is a novel potent mechanism-based SUMO-activating enzyme (SAE) inhibitor, selectively blocking SAE enzyme activity and total SUMOylation, thus decreasing cancer cell proliferation.
- Molecular Formula: C21H23BrN6O5S
- Molecular Weight: 551.42 g/mol
Minimum chemical purity: 95.0 %
- Solubility: Methanol (MeOH), Dimethylsulfoxide (DMSO)
Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor. By He et al., 2017, Nature Chemical Biology, 13(11), 1164-1171. doi: 10.1038/nchembio.2463
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