4LSC2956 ML-792 CAS# 1644342-14-2

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Catalog Number:4LSC2956
CAS #: 1644342-14-2
Name: ML-792; ((1R,2S,4R)-4-((5-(1-(3-bromobenzyl)-1H-pyrazole-3-carbonyl)pyrimidin-4-yl)amino)-2-hydroxycyclopentyl)methyl sulfamate
 

ML-792 is a novel potent mechanism-based SUMO-activating enzyme (SAE) inhibitor, selectively blocking SAE enzyme activity and total SUMOylation, thus decreasing cancer cell proliferation.

  • Molecular Formula: C21H23BrN6O5S
  • Molecular Weight: 551.42 g/mol
  • Specification:
    Minimum chemical purity: 95.0 %
  • Solubility: Methanol (MeOH), Dimethylsulfoxide (DMSO)

Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor. By He et al., 2017, Nature Chemical Biology, 13(11), 1164-1171. doi: 10.1038/nchembio.2463


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