4LSC3225 5′-Amino-Modifier C6 CAS# 114616-27-2
Catalog Number: 4LSC3225
CAS #: 114616-27-2
Name: 5′-Amino-Modifier C6; 6-(4-monomethoxytritylamino)hexyl-2-cyanoethyl-(N,N-diisopropyl)phosphoramidite
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5′-Internal & 3′-Amino Modifiers
5′-Amino modifiers are phosphoramidites which are used to produce a functional amine group on the 5′-terminus of oligonucleotides. The modifiers incorporate a C6 spacer with a primary amino group which can be used for subsequent conjugation to a vast majority of applications, such as dyes or labesls. The MMT protecting group can be removed on the DNA synthesizer by DCA treatment (usually 3% DCA/DCM). For cartridge purification, the final cleavage of the MMT group can be accomplished using a TFA solution (usually 2.5% TFA).
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