4LSC3230 3′-PT-Amino-Modifier C6 CPG
Catalog Number: 4LSC3230
CAS #: N/A
Name: 3′-PT-Amino-Modifier C6 CPG, N-(6-(O-(4,4′-Dimethoxytrityl))-hexyl)-(2-carboxamide)-phthalimidyl- lcaa-CPG
5′-Internal & 3′-Amino Modifiers
5′-Amino modifiers are phosphoramidites which are used to produce a functional amine group on the 5′-terminus of oligonucleotides. The modifiers incorporate a C6 spacer with a primary amino group which can be used for subsequent conjugation to a vast majority of applications, such as dyes or labesls. The MMT protecting group can be removed on the DNA synthesizer by DCA treatment (usually 3% DCA/DCM). For cartridge purification, the final cleavage of the MMT group can be accomplished using a TFA solution (usually 2.5% TFA).
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