4LSC3238 Biotin Phosphoramidite CAS# 147190-34-9
Catalog Number: 4LSC3238
CAS #: 147190-34-9
Name: Biotin Phosphoramidite; 2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-6-(5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexyl (2-cyanoethyl) diisopropylphosphoramidite
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5′ & Internal – Biotin Labeling
Biotin amidites are used in the 5′ labeling of oligonucleotides. Biotin labeling can be captured by avidin or streptavidin. The biotin phosphoramidite is a good alternative to the use of a biotin-NHS ester procedure. This compound allows multiple additons at the 5′-terminus of an oligonucleotide. An improvement in the use of multiple labeling has been achieved through the Biotin-TEG phosphoramidite. The mixed polarity of the triethyleneglycol linker is very useful for multiple additions as well as optimal capture by avidin and streptavidin.
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