4LSC3239 5′-Biotin Phosphoramidite CAS# 135137-87-0
Catalog Number: 4LSC3239
CAS #: 135137-87-0
Name: 5′-Biotin Phosphoramidite; [1-N-(4,4′–Dimethoxytrityl)-biotinyl-6-aminohexyl]-2-cyanoethyl-(N,N-diisopropyl)phosphoramidite
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5′ & Internal – Biotin Labeling
Biotin amidites are used in the 5′ labeling of oligonucleotides. Biotin labeling can be captured by avidin or streptavidin. The biotin phosphoramidite is a good alternative to the use of a biotin-NHS ester procedure. This compound allows multiple additons at the 5′-terminus of an oligonucleotide. An improvement in the use of multiple labeling has been achieved through the Biotin-TEG phosphoramidite. The mixed polarity of the triethyleneglycol linker is very useful for multiple additions as well as optimal capture by avidin and streptavidin.
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