4LSC3255 dSpacer-CE Phosphoramidite

Catalog Number: 4LSC3255
CAS #: N/A
Name: dSpacer-CE Phosphoramidite; 5′-O-Dimethoxytrityl-1′,2′-Dideoxyribose-3′-[(2-cyanoethyl)- (N,N-diisopropyl)]-phosphoramidite

5′- & 3′- Spacer Modifiers

Spacer modifiers are designed for internal and 5′-modifications. Spacer C-9 and spacer C-18 phosphoramidite are polyethyleneglycol-based that can be added sequentially when a longer arm is required. dSpacer allows the introduction of an abasic site into oligonucleotides. Spacer C-3 has an aliphatic linker.

  • Molecular Formula:  C35H45N2O6P

  • Molecular Weight: 620.7 g/mol
  • Specification:
    • HPLC – Identity is confirmed by comparison with a reference sample, Minimum purity
    • NMR – Purity is determined by 31P NMR and isomeric purity is veified by 1H NMR
    • Coupling Test – Coupling efficiency > 98%
    • Solution Test – 0.1M solution clear and free of particulate contamination
    • Loss on drying – volatile components are determined to be < 2%
    • Water content – determined to be < 0.4%
    • Certificate of Analysis are available for every batch, even for long past delivered products.