4LSC3260 3′-Glyceryl CPG
Catalog Number: 4LSC3260
CAS #: N/A
Name: 3′-Glyceryl CPG, 3-[(4,4′-Dimethoxytrityoxy)glyceryl-1-succinoyl]-long chain alkylamino-CPG
The 3′-Glyceryl-CPG is available with the standard Long Chain Alkyl Amine (LCAA) linker in both glass pore sizes, 500 and 1000 Angström. These supports are fully end-capped to ensure that CPG surface is inert in order to give clean and reproducible reaction profiles.
At the end of the oligonucleotide synthesis, the 3′-phosphoglyceryl terminus is oxidized by sodium periodate to form a 3′-phospho-glycaldehyde. The aldehyde may be further oxidized to the carboxylic acid. Either the aldehyde or the carboxylate may be used for subsequent conjugation to amine-containing products.
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