4LSC3321 D-erythro-Sphingosine-1-Phosphate (S1P) CAS# 26993-30-6
Catalog Number: 4LSC3321
CAS #: 26993-30-6
Name: Sphingosine-1-Phosphate (S1P), D-erythro-Sphingosine-1-Phosphate (S1P),
Sphingosine-1-Phosphate (S1P) is an endogenous second messenger involved in the control of cell proliferation and motility, and Ca2+ mobilization. Acts as an agonist at sphingosine-1-phosphate receptors (S1P1-5) and as an activator of GPR3, GPR6 and GPR12. Effectors regulated include p38 MAP kinase, PLC, adenylyl cyclase, myosin light chain phosphatase and focal adhesion kinase.
- Present as moiety constituent of sphingolipids
- Putative second messenger which mobilizes Ca from intracellular stores
- Activator of phospholipase D
- Stimulates growth of some fibroblasts
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