Sphingosines

Sphingosine-1-Phosphate (S1P) is an endogenous second messenger involved in the control of cell proliferation and motility, and Ca²⁺ mobilization. Acts as an agonist at sphingosine-1-phosphate receptors (S1P_1-5) and as an activator of GPR3, GPR6 and GPR12. Effectors regulated include p38 MAP kinase, PLC, adenylyl cyclase, myosin light chain phosphatase and focal adhesion kinase.

Major activities:

• Present as moiety constituent of sphingolipids
• Putative second messenger which mobilizes Ca from intracellular stores
• Activator of phospholipase D
• Stimulates growth of some fibroblasts

Please inquire about different chain-length analog !

• • Molecular Formula:  C₁₈H₃₈NO₅P
    

  • Molecular Weight: 379,48 g/mol
  • Specification:
    • Purity: >98% (TLC, HPLC)
      
    • Aspect: White powder
  • Long time storage: -18°C
  • Solubility: Methanol

Packed under inert gas, shipped at sub zero temperature