4LSC3323 Trimethyl Sphingosine (d18:1) CAS# 133561-52-1

Catalog Number: 4LSC3323
CAS #: 133561-52-1
Name: N,N,N-Trimethyl-D-erythro-Sphingosine sulphomethylate salt; Trimethyl Sphingosine (d18:1); (2S,3R,E)-1,3-dihydroxy-N,N,N-trimethyloctadec-4-en-2-aminium methyl sulfate


Trimethylsphingosine (TMS) is a synthetic sphingosine derivative.

Major activities:

  • Tumor growth inhibition (blocking membrane signaling)
  • Potent protein kinase C inhibition
  • Cardio protection
  • Inhibition of EGP receptor kinase
  • Inhibition of platet activation
  • Inhibition of adhesion of Le (X) and sialosyl expressing cells with platets and endothelial cells
  • Inhibition of PAF activation and PKC activity (more efficient than DMS)
    • Molecular Formula:  C22H47NO6S

    • Molecular Weight: 453.68 g/mol
    • Specification:
      • Purity: >98% (TLC, HPLC)
      • Aspect: White solid
    • Long time storage: -18°C

Packed under inert gas, shipped at sub zero temperature. 

Other Trimethylsphingosine salts can be made available, please inquire !