4LSC3851 cKK-E12 CAS# 1847446-19-8
Catalog Number: 4LSC3851
CAS #: 1847446-19-8
Related CAS #: 1432494-65-9 (racemic cKK-E12)
Name: (3S,6S)-3,6-bis(4-(bis((R)-2-hydroxydodecyl)amino)butyl)piperazine-2,5-dione; cKK-E12
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For R&D use only.
cKK-E12 is a potent cationic lipid that has been synthesized for lipid nanoparticles (LNPs) to deliver siRNA. LNP systems containing cKK-E12 has been shown be highly effective, non-toxic siRNA carriers both in vitro and in vivo with a wide therapeutic index. Additionaly, cKK-E12 based LNPs have been shown to be highly selective toward hepatocytes cells.
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